Mod GRF, GHRP-2 10mg (Blend)

Mod GRF, GHRP-2 10mg (Blend)

Growth hormone secretagogue receptor (GHSR) agonists like GHRP-2 are well known for their ability to produce large spikes in GH levels. These spikes, while providing a number of interesting and important benefits in animal models, are also short-lived because the half-life of most GHSR agonists is relatively short. To achieve long-term GH level increases, it is possible to use a GHRH analogue like modified GRF. This provides a long-term increase in both basal and peak GH levels, but nowhere near the kind of GH spike that a GHSR agonists provides. In addition, animal models show that GHRH analogues are susceptible to somatostatin interference, which can offset increases in GH levels.

To get the best of both worlds, research into combining GHSR agonists and GHRH analogues is being undertaken. One particularly researched combination is modified GRF with GHRP-2[1]. The synergy provides increased basal and peak levels of GH as well as measured spikes that boost the benefits of both peptides in ways that simply increasing one or the other cannot.

The net result of combining these peptides is improved GH release and substantial shifts in metabolism away from fat deposition. Lean body mass is increased substantially, insulin levels fall, and blood sugar becomes more regulated[2]-[4]. There is even evidence to show that both peptides, but particularly ipamorelin, can help to improve bone mineral density and bone health.